Evaluation of Effectiveness of Mitigation Strategies for COVID-19 Pandemic

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Video


Team Information

Team Members

  • Shanghong Xie, Postdoctoral Researcher, Biostatistics, Columbia University Mailman School of Public Health

  • Qinxia Wang, PhD Candidate, Biostatistics, Columbia University Mailman School of Public Health

  • Faculty Advisor: Yuanjia Wang, Professor, Biostatistics, Columbia University Mailman School of Public Health

Abstract

Coronavirus disease 2019 (COVID-19) pandemic is an unprecedented global public health challenge.In the United States (US), state governments have implemented various non-pharmaceutical interventions (NPIs),such as physical distance closure (lockdown), stay-at-home order, mandatory facial mask in public in response to the rapid spread of COVID-19. To evaluate the effectiveness of these NPIs, we propose a nested case-control design with propensity score weighting under the quasi-experiment framework to estimate the average intervention effect on disease transmission across states. We further develop a method to test for factors that moderate intervention effect to assist precision public health intervention. Our method takes account of the underlying dynamics of disease transmission and balance state-level pre-intervention characteristics. We prove that our estimator provides causal intervention effect under assumptions. We apply this method to analyze US COVID-19 incidence cases to estimate the effects of six interventions. We show that lockdown has the largest effect on reducing transmission and reopening bars significantly increase transmission.


Contact this Team

Contact: Shanghong Xie (use form to send email)

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